Ultrastructure of the ciliary muscle treated by organophosphate pesticide in beagle dogs.

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organophosphate pesticide in Beagle dogs

Organophosphate compounds, which are potent irreversible inhibitors of carboxylic esterases, including cholinesterase, have been extensively used as pesticides throughout the world, and many unfortunate incidents of acute intoxication have been reported (Grob and Harvey, I953; Goldman and Teitel, I958; Healy, 1959; Dinman, I964; Quinby, I964; Crowley and Johns, I966; DePalma, Kwalick, and Zuker...

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Histopathological study of canine optic nerve retina treated by organophosphate pesticide.

The fine structure of pathological changes was examined in the optic nerve and retina of beagle dogs after oral administration by capsule of the organophosphate pesticide ethylthiometon for 2 years. The optic nerve was invariably affected, and the number of myelinated axons markedly reduced. These were substituted for by delicate processes of astrocytes. Changes in the retina were mild and main...

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The organophosphate pesticide, Ethion, remains a major environmental contaminant in rural Australia and poses a significant threat to environmental and public health. The aerobic degradation of Ethion by mesophilic bacteria isolated from contaminated soils surrounding disused cattle dip sites was investigated. Two isolates, identified as Pseudomonas and Azospirillum species, were capable of bio...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1974

ISSN: 0007-1161

DOI: 10.1136/bjo.58.11.931